Blar i Bergen Open Research Archive på forfatter "Schmierer, Bernhard"

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    • An idiosyncratic zonated stroma encapsulates desmoplastic liver metastases and originates from injured liver 

      Fernández Moro, Carlos; Geyer, Natalie; Harrizi, Sara; Hamidi, Yousra; Söderqvist, Sara; Kuznyecov, Danyil; Tidholm Qvist, Evelina; Salmonson Schaad, Media; Hermann, Laura; Lindberg, Amanda; Heuchel, Rainer L.; Martín-Bernabé, Alfonso; Dhanjal, Soniya; Navis, Anna C.; Villard, Christina; del Valle, Andrea C.; Bozóky, Lorand; Sparrelid, Ernesto; Dirix, Luc; Strell, Carina; Östman, Arne; Schmierer, Bernhard; Vermeulen, Peter B.; Engstrand, Jennie; Bozóky, Béla; Gerling, Marco (Journal article; Peer reviewed, 2023)
      A perimetastatic capsule is a strong positive prognostic factor in liver metastases, but its origin remains unclear. Here, we systematically quantify the capsule’s extent and cellular composition in 263 patients with ...

    • Rapid genome editing by CRISPR-Cas9-POLD3 fusion 

      Reint, Ganna; Li, Zhuokun; Labun, Kornel; Keskitalo, Salla; Soppa, Inkeri; Mamia, Katariina Aino Inkeri; Tolo, Eero; Szymanska, Monika; Meza-Zepeda, Leonardo A.; Lorenz, Susanne; Cieslar-Pobuda, Artur Grzegorz; Hu, Xian; Bodin, Diana L; Staerk, Judith; Valen, Eivind Dale; Schmierer, Bernhard; Varjosalo, Markku; Taipale, Jussi; Haapaniemi, Emma Maria (Journal article; Peer reviewed, 2021)
      Precision CRISPR gene editing relies on the cellular homology-directed DNA repair (HDR) to introduce custom DNA sequences to target sites. The HDR editing efficiency varies between cell types and genomic sites, and the ...